Effect of Calmodulin on the Differren tiation and Migration of PC12 Cells

doi:10.7668/hbnxb.2011.01.005

Abstract

Abstract: To investigate the roles of calmodulin during neuronal differentiation and migration we checked PC 12cells by immunofluorescence staining and single cell tracking assay after NGF treatment. We found that calmodulinshowed a dense distribution pattern in top of PC 12 cells. Only a small percentage of the cells grown in treatmentcells. A single cell tracking experiment showed that calmodulin in PC12 cells could increase cell motility. The datasuggested that calmodulin may play an important role in differentiation and migration of PC12 cells.

Key words: Calmodulin, PC12 cell, W7, Differentiation, Migration

CLC Number:

YUAN Jun, LI Chao-jun. Effect of Calmodulin on the Differren tiation and Migration of PC12 Cells[J]. ACTA AGRICULTURAE BOREALI-SINICA, 2011, 26(1): 22-25. doi: 10.7668/hbnxb.2011.01.005.

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