Abstract: Perturbing systematic host network for Goose parvovirus (GPV) in natural infection were still unknown.Understanding pathogenic mechanism required that protein, enzymes and isozyme from goslings infected as manifestations of network properties, rather than simply as the result of individual variations.Here blood of experimentally GPV infected goslings were examined by biochemical analysis.The results indicated that the activity of protease, Est, POD, SOD, ALP, ADH, Amy, CAT, GPT and LDH from goslings infected GPV were higher 41%/63%, 30%/53%, 50%/14%, 36%/73%, 156%/142%, 1005%/22%, 36%/26%, 13%/51%, 60%/244%, 289%/139% than that of control group respectively.The content of IgG and IgM from goslings infected GPV were lower 50%, 40% than that of control group respectively, but protein was higher 50%.The isozyme of Est, SOD, ADH and Amy appeared 2, 2, 1, 3 new enzyme band respectively, but deleted 2 slow-zone Est isozyme band in the serum of goslings infected Goose parvovirus.The isozyme of Est, POD, SOD and Amy appeared 1, 2, 1, 2 new enzyme band in the blood corpuscle of goslings infected Goose parvovirus respectively.The isozyme of CAT, LDH, GPT and ALP appeared 7, 1, 3, 3 variation band in the blood of goslings infected GPV respectively.The isozyme of CAT and ADH defected fast-zone and slow-zone, fast-zone band in the blood corpuscle of goslings infected Goose parvovirus respectively.The isozyme of ALP defected slow-zone and fast-zone band in the serum and blood corpuscle of goslings infected GPV respectively.At the same time, it also showed that the 59 kDa protein band was a common feature of IgM/G in gosling, and IgG deleted still 258, 36 kDa protein in the blood of goslings infected Goose parvovirus.The protein were increased by 131, 86, 43, 33 kDa and 144, 104, 58, 53 kDa band in the serum and blood corpuscle of goslings infected Goose parvovirus respectively.There were deleted 1 slow-zone zymoprotein band in the serum of goslings infected GPV, and increased 2 slow-zone zymoprotein band in the blood corpuscle of goslings infected GPV.Those suggested that the interaction of GPV stress and host protein/enzymes and isozyme gene expression, through unique host dynamic balance of metabolic network directly or indirectly regulated cell disturbance susceptible performance.

Key words: Gosling, Goose parvovirus, Protein/Enzymes, Isozyme, Metabolic network

CLC Number: 

• S852.3