Progress on Research of Heat Shock Transcription Factors

doi:10.3321/j.issn:1000-7091.2000.Z1.006

Abstract

Abstract: Organisms respond to elevated temperatures and to chemical and ph ysiolo gical stresses by increasing the synthesis of heat shock proteins (HSPs). The exp ression of heat shock gene in eukaryotes is regulated by conserved heat shock tr anscription factor (HSF). HSF is present in a latent state under normal condition s; it is activated upon heat stress by induction of trimerization, highaffinity b inding to DNA and transcriptional activity. We described the HSF structure and th e regulation of its transcriptional activity.

Key words: Heat shock transcription factor, Domain, Regulation, Heat shock gene expression

LI Bing, LIU Hong tao, ZHOU Ren gang. Progress on Research of Heat Shock Transcription Factors[J]. ACTA AGRICULTURAE BOREALI-SINICA, 2000, 15(S1): 26-30. doi: 10.3321/j.issn:1000-7091.2000.Z1.006.

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