Study on Virulence to Larvae and Mammiferous Security of Recombinant Baculovirus (AcMNPV-BmKIT-Chi)

doi:10.7668/hbnxb.2007.05.039

Abstract

Abstract: AcMNPVs are specific insect pathogens used as selective biological insecticides on lepidopteran insects. In this paper, effectivity of virulence to larvae and security of recombinant baculovirus (AcMNPVBmKIT-Chi) to mouse were performed. Results suggested that the LC₅₀ of recombinant baculoviruses and wild type baculoviruses were 7.5×10² and 3.3×10⁴ PIBs/mL respectively. Recombinant baculoviruses were more virulent than wild type. Acute toxicity test and histologic section analysis showed that the alternation was not found when mice were fed with the two type of baculoviruses except the augmentation of splenic organs of the high dose group.

Key words: Recombinant baculovirus, Insecticidal activity, Biosafety

CLC Number:

S432.4+

FAN Xiao-jun, CAO Jian-bin, XU Cheng-gang, FU Yue-jun, ZHANG Zhi-yun, LIANG Ai-hua. Study on Virulence to Larvae and Mammiferous Security of Recombinant Baculovirus (AcMNPV-BmKIT-Chi)[J]. ACTA AGRICULTURAE BOREALI-SINICA, 2007, 22(5): 161-164. doi: 10.7668/hbnxb.2007.05.039.

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