Correlation Analysis Between BACE2 Gene Polymorphism and Growth Traits in Niangya Yak

doi:10.7668/hbnxb.20195661

Abstract

Abstract:

This study aimed to investigate the association between single-nucleotide polymorphisms(SNPs)in BACE2 gene and growth traits of Niangya yak,and to provide potential molecular markers for improving the growth performance of yak.Based on the re-sequencing data,two SNP sites(g.47,411T>C and g.81,108T>C)were detected in the BACE2 gene of Niangya yak.The genetic polymorphism of the two SNPs and the correlation between the two SNPs and growth traits of yaks were analyzed.Genetic polymorphism analysis showed that g.47,411T>C and g.81,108T>C loci were low polymorphic loci.The correlation results showed that the body weight and chest circumference traits of TT yaks with g.47,411T>C were significantly higher than those of CC yaks,and the body length of TT yaks was significantly higher than that of TC and CC yaks.The body weight and chest circumference of TT yaks with g.81,108T>C locus were significantly higher than those of CC yaks.The body length of TT yaks was significantly higher than that of TC yaks,and the body length of TC yaks was significantly higher than that of CC yaks.In conclusion,the g.47,411T>C and g.81,108T>C loci of the BACE2 gene had significant effects on growth traits of Niangya yak.

Key words: Niangya yak, BACE2 gene, SNP, Genetic polymorphism, Growth trait

CLC Number:

S823.85

ZHANG Juanxiang, REN Wenwen, YU Daoning, XU Yefen, OJIE Ciren, LIANG Chunnian. Correlation Analysis Between BACE2 Gene Polymorphism and Growth Traits in Niangya Yak[J]. Acta Agriculturae Boreali-Sinica, 2025, 40(S1): 307-312. doi: 10.7668/hbnxb.20195661.

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References 29

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位点 Locus	引物序列(5'-3') Primer sequences (5'-3')	产物长度/bp Product length	退火温度/℃ Annealing temperature
SNP g.47,411T>C	F: GGTAATAGGTGTCAGTGAGATG	501	58.7
	R: GGAGGTTCTGGCTTCTTCT
SNP g.81,108T>C	F: TGCTTACCTGCCTTATCTGTTC	539	54.0
	R:AAGAGGTTGATTGGAAGGAAGAG

位点 Locus	引物序列(5'-3') Primer sequences (5'-3')	产物长度/bp Product length	退火温度/℃ Annealing temperature
SNP g.47,411T>C	F: GGTAATAGGTGTCAGTGAGATG	501	58.7
	R: GGAGGTTCTGGCTTCTTCT
SNP g.81,108T>C	F: TGCTTACCTGCCTTATCTGTTC	539	54.0
	R:AAGAGGTTGATTGGAAGGAAGAG

位点 Locus	基因型频率(数量) Genotype frequency (quantity)			等位基因频率 Allele frequency		P	PIC	He	Ne
位点 Locus	TT	TC	CC	T	C	P	PIC	He	Ne
g.47,411T>C	0.021 (4)	0.090(17)	0.889(168)	0.063	0.927	P<0.01	0.11	0.12	1.13
g.81,108T>C	0.020 (4)	0.086 (17)	0.894(177)	0.063	0.937	P<0.01	0.11	0.12	1.13

位点 Locus	基因型频率(数量) Genotype frequency (quantity)			等位基因频率 Allele frequency		P	PIC	He	Ne
位点 Locus	TT	TC	CC	T	C	P	PIC	He	Ne
g.47,411T>C	0.021 (4)	0.090(17)	0.889(168)	0.063	0.927	P<0.01	0.11	0.12	1.13
g.81,108T>C	0.020 (4)	0.086 (17)	0.894(177)	0.063	0.937	P<0.01	0.11	0.12	1.13

SNPs	基因型 Genotype	体质量/cm Body weight	体高/cm Body height	体长/cm Body slanting length	胸围/cm Chest circumference
g.47,411T>C	TT	247.11±19.21a	112.50±4.04a	131.00±4.69a	167.75±3.3a
	TC	223.22±43.15ab	111.29±5.14a	122.59±6.75b	160.65±13.72ab
	CC	187.56±42.07b	108.03±9.26a	116.01±9.52b	153.50±12.99b
g.81,108T>C	TT	247.31±19.58a	112.00±4.24a	131.50±5.45a	167.50±3.11a
	TC	225.49±45.08ab	111.41±5.14a	122.71±6.75b	161.29±14.11ab
	CC	190.37±42.77b	106.42±6.14a	114.74±8.14c	155.27±13.29b

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