Abstract: On the basis of detect ion of FUT I genotypes of Laiwu Black Pigs and Yorkshire using PCR-RFLP,small intestinal epithelium cells of different genotypes,susceptive genotype and resistant genotype,were selected to test resistance and adhesion capability to the wild type enterotoxigenic Escherichia coli (ETEC F18).Because of several reasons,the pigs orally taken E.coli F18 did not catch the diseases,and it was impossible to judge their resistance to <>E.coli F18.The result dedicated that E.coli F18 could adhere to all the small intestinal epithelium cells of suscept ive genotype and not to the small intestinal epithelium cells of resistant genotype.There was not difference of adhesion capability in Laiwu Black Pigs and Yorkshire.But in the pig product ion,post-weaning diarrhea and edema disease seldom happened in Laiwu Black Pigs.Therefore,except of FUT I gene,perhaps there are other mutation and resistant gene of E.coli F18 in Laiwu Black Pigs and other indigenous pig breeds of China.

Key words: Laiwu black pigs, E.coli expressing F18 fimbriae, FUT I gene, Small intestinal Epithelium cell, Adhesion

CLC Number: 

• Q78