模拟移动床技术在生化领域的应用研究进展

doi:10.7668/hbnxb.2006.S3.019

摘要/Abstract

摘要： 模拟移动床技术作为一种新型色谱分离技术, 应用日益广泛。文章介绍了模拟移动床技术的发展情况及其工作原理, 并详细介绍了模拟移动床技术在生化产品分离中的研究进展和应用情况。

Abstract: Simulated moving bed (SMB) is a new separation technology. The history of its development and principle operation are introduced in this paper. The applications of SMB in bioseparation are reviewed.

Key words: Simulated moving bed, Bioseparation, Application

中图分类号:

Q946

蔡恒, 朱庆平, 陆彬, 王涛, 万红贵. 模拟移动床技术在生化领域的应用研究进展[J]. 华北农学报, 2006, 21(S3): 91-95. doi: 10.7668/hbnxb.2006.S3.019.

CAI Heng, ZHU Qing-ping, LU Bin, WANG Tao, WAN Hong-gui. The Application of Simulated Moving Bed in Bioseparation[J]. ACTA AGRICULTURAE BOREALI-SINICA, 2006, 21(S3): 91-95. doi: 10.7668/hbnxb.2006.S3.019.

http://www.hbnxb.net/CN/Y2006/V21/IS3/91

参考文献

[l]Broughton D B,Gerhold C G. Continuous sorption process employing fixed bed of sorbent and moving inlets and outlets[P]. US2985589,1961.
[2] Broughton D B.Production-scale adsorptive separations of liquid mixtures by simulated moving-bed technology[J],Sep Sci Technol,1984,19(11-12): 723-736.
[3] 达世禄.色谱学导论[M].武汉：武汉大学出版社,1999.
[4] Zang Y,Wankat P C. Variable Flow Rate Operation for Simulated Moving Bed Separation Systems: Simulation and Optimization[J].Ind Eng Chem Res,2003,42 (20): 4840-4848.
[5] Juza M,Mazzotti M,Morbidelli M. Simulated moving-bed chromatography and its application to chirotechnology[J]. Trends in Biotechnology,2000,18(3): 108-118.
[6] Beste Y A,Usso M,Wozny G,et al. Optimization of simulated moving bed plants with low efficient stationary phases: separation of fructose and glucose[J]. Journal of Chromatography A,2000,868(2): 169-188.
[7] BarkerPE,GanetsosG.Chemicaland biochemical separation using preparative and large scale batch and continuous chromatography[J].Separation and Purification Methods,1988,17(1): 1-65.
[8] Wooley R,Ma ZT Wang N H L. A Nine-Zone Simulating Moving Bed for the Recovery of Glucose and Xylose from Biomass Hydrolyzate[J].Ind Eng Chem Res,1998,37 (9): 3699-3709.
[9] Coelho M S,Azevedo DCS,Teixeira J A. Dextran and fructose separation on an SMB continuous chromatographic unit[J]. Biochemical Engineering Journal,2002,12(3):215-221.
[10] Bubnik Z,Pour V,Gruberova A,et al. Application of continuous chromatographic separation in sugar processing[J]. Journal of Food Engineering,2004,61 (4): 509-513.
[11] 蔡宇杰,丁彦蕊,须文波,等.线性条件下木糖醇母液模拟移动床色谱分离[J].无锡轻工大学学报,2002,21 (4)：372-375.
[12] 蔡宇杰,丁彦蕊,张大兵,等.基于浮点编码的遗传算法优化模拟移动床色谱分离木糖醇母液m.色谱,2003,21 (3)： 206-209.
[13] 江波,王璋,杨瑞金,等.高纯度低聚果糖的研制[J].中国食品添加剂,1999,(3)： 1-7.
[14] Van Walsem H J,Thompson M C.Simulated moving bed in the production of lysine[J].Joumal of Biotechnology,1997,59(1-2): 127-132.
[15] Robatjazi S M,Shojaosadali S A,Karbasy S M. Purification of L-Lysine in Simulated Moving Bed and Fix -Bed Chromatography[J]. Chinese Journal of C hroma tography,2004,22(4): 431 -434.
[16] 龙万凯.我国赖氨酸工业技术新进展[J].化学工程,2003,31(5): 74-78.
[17] W". D J,Xie Y,Ma Z,et al. Design of Simulated Moving Bed Chromatography for Amino Acid Separations[J]. Ind Eng Chem Res,1998,37(10): 4023-4035.
[18] 万红贵,方煜宇,叶慧.模拟移动床技术分离缬氨酸和丙氨酸[J].食品与发酵工业,2005,31(12):50-53.
[19] Houwing J,Billiet Hugo A H,van der Wielen Luuk A M.Optimization of azeotropic protein separations in gradient and isocratic ion -exchange simulated moving bed chromatography[J].Joumal of Chromatography A,2002’ 944(1-2)： 189-201.
[20] Houwing J,van Hateren Stef H,Billiet Hugo A H,et al. Effect of salt gradients bn the separation of dilute mixtures of proteins by ion -exchange in simulated moving beds[J]. Journal of Chromatography A,2002,952(1-2)： 85-98.
[21] Jonatan A,Bo M. Simulated moving bed technology with a simplified approach for protein purification: Separation of lactoperoxidase and lactoferrin from whey protein concentrate[J]. Journal of Chromatography A,2006,1107(1-2)： 88-95.
[22] Ludmila Gueorguieva,Luis Felipe Vallejo,Ursula Rinas,et al.Discontinuous and continuous separation of the monomeric and dimeric forms of human bone morphogenetic protein-2 from renaturation batches[J]. Journal of Chromatography A,2006,1135(2): 142-150.
[23] Lee H J,Xie Y,Koo Y M,et al. Separation of Lactic Acid from Acetic Acid Using a Four -Zone SMB[J]. Biotechnol Prog,2004,20(1): 179-192.
[24] 张丽华,肖国勇,高丽娟,等.模拟移动床色谱分离替考拉宁条件研究[jj.化学世界,2002,(3):130-132.
[25] 高丽娟,张玄波,宋峰,等.替考拉丁工业色谱条件选择⑴.鞍山科技大学学报,2004,27(I):20-22.
[26] 吴粦华,孙洪贵.连续逆流离子交换技术及其在抗生素生产中的应用[J].福建化工,2003,(1):13-16.
[27] Schulte M,Ditz R,Devant R M,et al. Comparison of the specific productivity of different chiral stationary phases used for simulated moving -bed chromatography[J]. Journal of Chromatography A,1997,769(1): 93-100.
[28] Pais L S,Loureiro J M,Rodrigues A E. Modeling simulation and operation of a simulated moving bed for continuous chromatographic separation of 1,1 ^ -bi-2-naphthol enantiomers[J]. Journal of Chromatography A,1997,769(1): 25-35.
[29] Michael Schulte,JochenStrubeb.Preparativeenantiosep-aration by simulated moving bed- chromatography[J]. Journal of Chromatography A,2001,906(1-2): 399-416.
[30] Xie Y,Hritzko B,Chin C Y_ Separation of fTC-Ester Enantiomers Using a Simulated Moving Bed[J]. Ind Eng Chem Res,2003,42(17):4055-4067.
[31] Gotlschlich Norbert,Kasche Volker. Purification of monoclonal antibodies by simulated moving —bed chromatography[J]. Journal of Chromatography A,1997,765(2)： 201-206.
[32] Schulte M,Luhring N,Keil A,et al. Purification of DMT -On Oligonucleotide by Simulated Moving -Bed (SMB) Chromatography[J]. Org Process Res Dev,2005,9 (2):212-215.
[33] Temesv6ri K,Aranyi A,Csukds,el al. Simulated Moving Bed Chromatographic Separation of a Two -Component Steroid Mixture[J].Chromatographia,2004T 60(L)：S189-S199.
[34] Xie Y,Mun S Y,Wang NHL. Startup and Shutdown Strategies of Simulated Moving Bed for Insulin Purification[J]. Ind Eng Chem Res,2003,42(7): 14141425.
[35] Mun S,Xie Y,Wang NHL Robust Pinched-Wave Design of a Size -Exclusion Simulated Moving -Bed Process for Insulin Purification[J]. Ind Eng Chem Res,2003,42(13)；3129-3143.
[36] Mun S,Wang N H L.Insulin Wave Dynamics in Size-Exclusion Simulated Moving Bed with Residence Time Control[J].Ind Eng Chem Res,2006,45(4): 1454-1465.
[37] Galalea Paredes,Marco Mazzotti,Joachim Stadler,et al. SMB Operalion for Three -Fraction Separations: Purillcalion of Plasmid DNA[J]. Adsorption,2005,11(1): 841-845.
[38] Lu Yubin,Yang Yiwen,Wu Pingdong. Separation of phosphatidylcholine from soybean phospholipids bysimulated moving bed.Joumal of Zhejiang University SCIENCE B,2006,7(7)：559-564.
[39] 李勃,肖国勇,林炳昌,等.模拟移动床分离紫杉醇[J].鞍山钢铁学院学报,2000,23(4)： 244-248.
[40] 张丽华,高丽娟,林炳昌.模拟移动床色谱提纯槲皮素[J].鞍山钢铁学院学报,2002,25(2)： 108-111.
[41] 高丽娟,刘望才,张伟,等.银杏内酯B的纯化[J]. 精细化工,2004,21(6): 418-420.
[42] 丛景香,林炳昌.甘草甙的分离纯化及鉴定[J].精细化工,2005,22(12)： 912-915.
[43] 高丽娟,刘望才,全艳玲,等.纯化银杏总内酯的新工艺[J].化学世界,2005,(12): 711-714.

[1]	孟祥坤, 于新, 朱超, 胡兆平, 范玲超. 解磷微生物研究与应用进展[J]. 华北农学报, 2018, 33(S1): 208-214.
[2]	马鹏, 李林杰, 常秋燕, 王悦萦, 郭富城, 刘萍, 马晓霞, 马忠仁. BVDV SYBR Green Ⅰ荧光定量PCR方法与RT-PCR方法的建立与应用[J]. 华北农学报, 2017, 32(S1): 49-53.
[3]	兰进好, 宋朝玉. 一个抗玉米粗缩病新种质QR-001的抗性遗传分析[J]. 华北农学报, 2014, 29(S1): 89-93.
[4]	何盛莲, 雷振生, 吴政卿, 赵献林, 方保停, 杨攀, 杨会民, 何宁, 王美芳, 李巍. 小麦高分子量麦谷蛋白亚基基因1By8的分子检测和应用[J]. 华北农学报, 2010, 25(4): 35-39.
[5]	肖相政, 刘可星, 张志红, 刘亮, 廖宗文. 生物有机肥对烤烟生长及相关防御性酶活性的影响[J]. 华北农学报, 2010, 25(1): 175-179.
[6]	张德双, 陈斌, 张凤兰, 余阳俊, 赵岫云, 于拴仓, 徐家炳. 一种紫色大白菜细胞质不育系的分子鉴定[J]. 华北农学报, 2009, 24(3): 174-178.
[7]	李和平, 吴发兴, 李晓成, 陈德坤. 猪繁殖与呼吸综合征的套式PCR方法建立及应用[J]. 华北农学报, 2009, 24(1): 115-118.
[8]	李国鹏, 何红艳, 黄家雄, 罗心平, 李贵平, 杨仕贵, 李树维, 黄健, 郭容琦. 分子标记技术在咖啡育种上的应用(英文)[J]. 华北农学报, 2008, 23(S2): 129-132.
[9]	彭博, 刘孟军, 刘平, 宁强, 苗利军. 果树2n配子研究进展[J]. 华北农学报, 2008, 23(S1): 54-58.
[10]	郭树春, 安玉麟, 李素萍, 孙瑞芬, 张艳芳, 张启辰, 闫素丽. DNA分子标记在作物种质资源中的应用进展[J]. 华北农学报, 2007, 22(S3): 91-97.
[11]	尹玲莉, 杨凤环, 侯晓杰, 杜绍华. 化学药剂诱导植物抗病性研究进展[J]. 华北农学报, 2007, 22(S1): 43-46.
[12]	李宗新, 王庆成, 齐世军, 刘开昌, 刘霞, 张彗. 控释肥对玉米高产的应用效应研究进展[J]. 华北农学报, 2007, 22(S1): 127-130.
[13]	李若楠, 张彦才. 转基因动物技术及其应用[J]. 华北农学报, 2007, 22(S1): 181-184.
[14]	贾学文, 闫伟, 白淑兰, 邵东华, 王铁牛. 根际土壤微生物最佳分离条件筛选研究[J]. 华北农学报, 2007, 22(6): 147-151.
[15]	赵灵芝, 陈春原, 赵勇, 李晓燕, 希日格乐, 张海燕. 果树立体生态种植模式的应用[J]. 华北农学报, 2006, 21(S3): 32-36.

选择文件类型/文献管理软件名称

选择包含的内容